BRIEF

on The Vanguard Group, Inc. (isin : US12572Q1058)

The Vanguard Group's Stake in Mural Oncology plc

The Vanguard Group, Inc. has disclosed its position regarding its interests in Mural Oncology plc, in line with Rule 8.3 of the Irish Takeover Panel Act, 1997. As of May 29, 2025, Vanguard holds 772,885 $0.01 ordinary shares, equating to a 4.48% interest in Mural Oncology. This disclosure does not include any interests in additional parties related to the offer.

Vanguard reported a minor transaction involving the sale of 18 shares at a price of $2.64 per unit. There are no cash-settled or stock-settled derivative positions to disclose, and no supplemental Form 8 is attached to this disclosure.

No indemnity or option arrangements exist that might influence dealings. Similarly, no agreements affect voting rights or future securities transactions. The document also confirms that there are no other relevant dealings or new securities transactions.

R. H.

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