The Vanguard Group's Position on Mural Oncology plc

The Vanguard Group, Inc. has disclosed its current interests in the securities of Mural Oncology plc under Rule 8.3 of the Irish Takeover Panel Act, 1997. As of July 10th, 2025, Vanguard holds 772,675 ordinary shares, amounting to a 4.47% stake in Mural Oncology. This marks their current significant shareholding in Mural Oncology, represented by $0.01 ordinary shares.

No dealings were disclosed apart from the sale of 64 such shares at a price of $2.48 USD each. Furthermore, the document clarifies that there are no cash-settled or stock-settled derivatives or additional purchase agreements pertaining to these securities. Vanguard also confirms the absence of any indemnity or other dealing arrangements, as well as agreements concerning options or derivatives related to voting rights or security acquisition or disposal.