BRIEF

on The Vanguard Group, Inc. (isin : US12572Q1058)

The Vanguard Group Discloses Position in Mural Oncology plc

The Vanguard Group, Inc. has submitted a Form 8.3 in relation to Mural Oncology plc as per the Irish Takeover Panel Act, 1997. The disclosure, dated 3 November 2025, confirms The Vanguard Group's interest in Mural Oncology plc. The disclosure indicates The Vanguard Group holds 288,683 of Mural Oncology's $0.01 ordinary shares, which represents a 1.67% interest.

The filing does not report any cash-settled or stock-settled derivative positions related to Mural Oncology. However, there was a recorded sale of 224 of the $0.01 ordinary shares at 2.09 USD per unit. The document confirms that there are no indemnity or other dealing arrangements tied to this disclosure.

No additional supplemental forms or agreements impacting the voting rights or acquisition plans of Mural Oncology's shares have been attached or disclosed.

R. H.

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