The Vanguard Group Discloses Position in Mural Oncology plc

The Vanguard Group, Inc. submitted a Form 8.3 revealing its stake in Mural Oncology plc under the Irish Takeover Panel rules. As of October 22, 2025, Vanguard holds 288,843 ordinary shares, representing a 1.67% interest in Mural Oncology. This disclosure is crucial due to regulations requiring parties with over 1% interest in relevant securities to report their holdings and activities.

The form indicates Vanguard made a purchase of 80 ordinary shares at 2.10 USD per share. No other transactions, such as cash-settled derivatives or stock-settled derivatives, have been disclosed regarding these shares.

Further, there are no indemnity or option arrangements, nor any agreements or understandings related to options or derivatives between Vanguard and any other parties involved.