The Vanguard Group Discloses Position in Mural Oncology

The Vanguard Group, Inc. has released Form 8.3 in compliance with the Irish Takeover Panel Act. This disclosure pertains to their position in Mural Oncology plc. As of October 20, 2025, Vanguard holds 288,763 ordinary shares at 1.67% of relevant securities. This indicates a significant interest in Mural Oncology.

In recent dealings, Vanguard sold 48 of these shares at a price of 2.09 USD per unit. The form shows no activities in cash-settled or stock-settled derivatives. Vanguard confirms no existing indemnity, agreement or arrangement concerning the securities beyond this disclosure.

This announcement aligns with the rules governing stakes of 1% or more in relevant securities of companies under consideration for a potential takeover or other significant corporate event by the Irish Takeover Panel.