Biophytis Receives EUR980,000 DeepTech Funding from BPI France for the
development of Macuneos (BIO201) in dry AMD
* DeepTech funding supports advanced and highly differentiating biotech
projects with significant commercial potential
* Biophytis plans to initiate Phase 1 clinical trial in the second half of
Paris, France, Cambridge (Massachusetts, United States), April 29 2021, 8AM CET
- Biophytis SA (Euronext Growth Paris: ALBPS), a clinical-stage biotechnology
company focused on the development of therapeutics aimed at slowing the
degenerative processes associated with aging and improving functional outcomes
for patients suffering from age-related diseases, including severe respiratory
failure in patients suffering from COVID-19, today announces it was granted a
non-dilutive funding of EUR980,000 from the public investment bank BPI France's
DeepTech program, for its MACA program of Macuneos (BIO201) in dry Age-Related
Macular Degeneration (AMD).
The DeepTech program aims to boost highly innovative and breakthrough projects
emerging from fundamental research with attractive dedicated financing tools.
The funding consists of a conditional advance of EUR600,000 and a grant of
EUR380,000 which will complement existing financing for preclinical studies of
Biophytis' MACA clinical program in treatment of dry AMD, an age-related
degeneration of the macula, the central part of the retina. AMD is one of the
leading causes of irreversible vision loss and blindness in people over the age
Stanislas Veillet, President and CEO of Biophytis, said: "We are pleased with
this funding award, which recognizes the potential of Biophytis' Macuneos
(BIO201), which has demonstrated promising results in preclinical studies.
There is still no available treatment for dry AMD and the loss of vision has a
significant impact on patients' quality of life. Macuneos (BIO201) has the
potential to address a major unmet medical need and we look forward to further
investigating it in clinical phases."
Biophytis plans to initiate a Phase 1 clinical trial (MACA-PK) in healthy
volunteers in the second half of 2021, subject to regulatory review and
approval as well as COVID-19-related delays and the impact of the pandemic on
Macuneos (BIO201) is an orally administered small molecule in development for
the treatment of diseases of the retina, or retinopathies. It is a
plant-derived pharmaceutical-grade purified 9 cis-norbixin, or norbixin.
Biophytis has completed preclinical cellular and animal studies of Macuneos
(BIO201) for the treatment of retinopathies.
Biophytis believes that the results from preclinical studies support continued
investigation to whether Macuneos (BIO201) may stimulate biological resilience
and protect the retina against phototoxic damage that leads to vision loss. Dry
AMD is a common eye disorder among people over the age of 50 that affects
central vision, impairing functions such as reading, driving, and facial
recognition, and has a major impact on quality of life and the ability to live
independently. There are currently no approved drugs for dry AMD. Based on
estimates from publicly available information, AMD affects approximately 8.5%
of the global population (ages 45 to 85) and is expected to increase over time
as the population ages.
Biophytis SA is a clinical-stage biotechnology company specialized in the
development of therapeutics that are aimed at slowing the degenerative
processes associated with aging and improving functional outcomes for patients
suffering from age-related diseases, including severe respiratory failure in
patients suffering from COVID-19.
Sarconeos (BIO101), our leading drug candidate, is a small molecule,
administered orally, being developed as a treatment for sarcopenia in a Phase 2
clinical trial in the United States and Europe (SARA-INT). It is also being
studied in a clinical two-part Phase 2-3 study (COVA) for the treatment of
severe respiratory manifestations of COVID-19 in Europe, Latin America, and the
US. A pediatric formulation of Sarconeos (BIO101) is being developed for the
treatment of Duchenne Muscular Dystrophy (DMD).
The company is based in Paris, France, and Cambridge, Massachusetts. The
company's common shares are listed on Euronext Growth (Ticker: ALBPS -ISIN:
FR0012816825) and ADSs are listed on Nasdaq Capital Market (Ticker BPTS - ISIN:
For more information visit www.biophytis.com
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Biophytis Contact for Investor Relations
Evelyne Nguyen, CFO
Life Sci Advisors
Sophie Baumont/Chris Maggos
T: +33 6 27 74 74 49